Dr. Abhinandan Dilipkumar Hudwekar
POSITIONAssistant Professor
DEPARTMENTSchool of Pharmacy
Bio
An experienced Pharmaceutical Chemist with a strong background in drug discovery and medicinal chemistry, currently working as an Assistant Professor. Expertise in the design and multi-step synthesis of small molecule ligands, inhibitors, and PROTACs for challenging therapeutic targets. Proficiency in Structure-Activity Relationship (SAR) analysis and the development of novel, transition metal-free synthetic methodologies
Awards and Achievements
- GATE-2009
- NIPER-JEE
Areas of Research
Key areas:
- Medicinal Chemistry,
- Drug discovery
Research and Publications
- Abhinandan D. Hudwekar, Pankul Kotwal, Mohd. Ishaq Dar, Shilpi Balgotra, Ashish Dogra, Jaspreet Kour, Santosh S. Chobe, Utpal Nandi, Sajad Hussain Syed, Sanghapal D. Sawant, Pyrazolopyrimidinone Based Selective Inhibitors of PDE5 for the Treatment of Erectile Dysfunction, Chem. Biodiversity, 2023, 20, e202200707.
- Abhinandan D. Hudwekar, Praveen K. Verma, Jaspreet Kour, Shilpi Balgotra, Sanghapal D. Sawant, Transition Metal-Free Oxidative Coupling of Primary Amines in Polyethylene Glycol at Room Temperature: Synthesis of Imines, Azobenzenes, Benzothiazoles and Disulfides, Eur. J. Org. Chem., 2019, 1242-1250.
- Abhinandan D. Hudwekar, G. Lakshma Reddy, Praveen K. Verma, Sorav Gupta, Ram A. Vishwakarma, Sanghapal D. Sawant, Transition metal–free single step approach for arylated pyrazolopyrimidinones and quinazolinones using benzylamines/benzylalcohols/benzaldehydes, ChemistrySelect, 2017, 2, 4963– 4968.
- Sanghapal D. Sawant*, Abhinandan D Hudwekar, K.A. Arvinda Kumar, Vunnam Venkateshwarlu, Parvinder Pal Singh, Ram A. Vishwakarma, Ligand- and base-free synthesis of phenols by rapid oxidation of arylboronic acids using iron(III) oxide, Tetrahedron lett., 2014, 55, 4, 811-814.
- G Lakshma Reddy, Mohd Ishaq Dar, Abhinandan D Hudwekar, Priya Mahajan, Amit Nargotra, Adil Manzoor Baba, Utpal Nandi, Priya Wazir, Gurdarshan Singh, Ram A Vishwakarma, Sajad Hussain Syed, Sanghapal D Sawan, Design, synthesis and biological evaluation of pyrazolopyrimidinone based potent and selective PDE5 inhibitors for treatment of erectile dysfunction, Bioorg. Chem., 2019, 89, 103022.
- Mahesuni Srinivas, Abhinandan D. Hudwekar, Vunnam Venkateswarlu, G. Lakshma Reddy, K.A. Aravinda Kumar, Ram A. Vishwakarma, Sanghapal D. Sawant, A metal-free approach for transamidation of amides with amines in aqueous media, Tetrahedron Lett., 2015, 56, 33, 4775-4779.
- Vunnam Venkateswarlu, Jaspreet Kour, K. A. Aravinda Kumar, Praveen Kumar Verma, G. Lakshma Reddy, Yaseen Hussain, Aliya Tabassum, Shilpi Balgotra, Sorav Gupta, Abhinandan D. Hudwekar, Ram A. Vishwakarma, Sanghapal D. Sawant, Direct N-Heterocyclization of Hydrazines to Access Styrylated Pyrazoles: Synthesis of 1,3,5- Trisubstituted Pyrazoles and Dihydropyrazoles, RSC Adv., 2018, 8, 26523- 26527.
